Molecular Biology of the Parathyroid PDF Download. Download free ebook of Molecular Biology of the Parathyroid in PDF format or read online by Tally Naveh-Many 9780387275307 Published on 2007-02-26 by Springer Science & Business Media
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described.
This Book was ranked at 28 by Google Books for keyword Molecular Biology.
Book ID of Molecular Biology of the Parathyroid's Books is G69_l3qqye4C, Book which was written by Tally Naveh-Many have ETAG "L28LJl1zYL4"
Book which was published by Springer Science & Business Media since 2007-02-26 have ISBNs, ISBN 13 Code is 9780387275307 and ISBN 10 Code is 0387275304
Reading Mode in Text Status is false and Reading Mode in Image Status is true
Book which have "199 Pages" is Printed at BOOK under CategoryScience
Book was written in en
eBook Version Availability Status at PDF is true and in ePub is false
Book Preview
Download Molecular Biology of the Parathyroid PDF Free
Download Molecular Biology of the Parathyroid Books Free
Download Molecular Biology of the Parathyroid Free
Download Molecular Biology of the Parathyroid PDF
Download Molecular Biology of the Parathyroid Books
No comments:
Post a Comment