Genetics of Bone Biology and Skeletal Disease PDF Download. Download free ebook of Genetics of Bone Biology and Skeletal Disease in PDF format or read online by Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi 9780128041987 Published on 2017-10-31 by Academic Press
Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder
This Book was ranked at 23 by Google Books for keyword Genetics.
Book ID of Genetics of Bone Biology and Skeletal Disease's Books is tmx_CwAAQBAJ, Book which was written by Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi have ETAG "9ATO3q1kUD4"
Book which was published by Academic Press since 2017-10-31 have ISBNs, ISBN 13 Code is 9780128041987 and ISBN 10 Code is 0128041986
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Book which have "878 Pages" is Printed at BOOK under CategoryMedical
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Download Genetics of Bone Biology and Skeletal Disease PDF Free
Download Genetics of Bone Biology and Skeletal Disease Books Free
Download Genetics of Bone Biology and Skeletal Disease Free
Download Genetics of Bone Biology and Skeletal Disease PDF
Download Genetics of Bone Biology and Skeletal Disease Books
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